Inflammatory disease of the THYROID GLAND due to autoimmune responses leading to lymphocytic infiltration of the gland. It is characterized by the presence of circulating thyroid antigen-specific T-CELLS and thyroid AUTOANTIBODIES. The clinical signs can range from HYPOTHYROIDISM to THYROTOXICOSIS depending on the type of autoimmune thyroiditis.
More details about the regions are available here.
Region | Position | Genes | Markers | Diseases |
---|---|---|---|---|
ATD 1p13.2 | chr1:113296527-114009223 | PTPN22 | rs2476601 | |
ATD 1p36.32 | chr1:2431888-2879054 | MMEL1 | rs2843403 | |
ATD 2q33.2 | chr2:203768727-203951852 | ICOS CTLA4 | rs11571297 | |
ATD 3q28 | chr3:188351572-188422865 | LPP | rs13093110 | |
ATD 6q15 | chr6:90097116-90319078 | BACH2 | rs72928038 | |
ATD 10p15.1 | chr10:5988280-6129961 | IL2RA | rs706779 | |
ATD 11q21 | chr11:95537638-95599614 | rs4409785 | ||
ATD 14q31.1 | chr14:80636325-81113845 | TSHR | rs2300519 |
Study ID | Title | Publication | Diseases |
---|---|---|---|
018 | Immunochip | Cooper Hum. Mol. Genet., 2012-08-24 |