CASP8

Overview

Gene	CASP8
Biotype	protein_coding
Description	caspase 8
Synonyms	ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5;
Location	chr2:201233443-201287711

Jbrowse

External Links

Ensembl	ENSG00000064012
Entrez	841
Hgnc	1509
Hprd	03459
Mim	601763
Swissprot	Q14790
Trembl	A0A024R3Z8 C9JB29 E7EVN1 E7EQ06 F8WF39 E7ETB7 E7EQ01 H7BZM4 H7C0E2 A0A0A0MS31
Vega	OTTHUMG00000132821

Criteria

CASP8 meets the following criteria:

Criteria Name

Details

Disease Tags

Candidate Gene in a Region

Candidate Gene for a Study

Gene is located within a Region

Study

Studies containing regions of association that span this gene are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

Study	Publication	Disease	Region	Marker	Alleles	P-value	OR	MAF	Gene(s)

Publications

PMID	Title	First Author	Journal	Disease(s)	Date

Interactions

Interactions for the gene CASP8 are derived from IntAct and BioPlex.

Interactor	PMID	Source

Gene Sets

Gene sets for the gene CASP8 are derived from MSigDB

Name	Genes

Phenotype Links

Organism	Gene	Phenotype	Resources
Mouse	MGI:1261423	MGI:1261423	IMPC