Overview

IDAllelesLocationGenome BuildSource
rs102275T/Cchr11: 6179033138dbsnp146
rs102275T/C chr11: 61557803 37dbsnp146_grch37
rs102275T/C chr11: 61790331 38ImmunoChip
rs102275T/C chr11: 61557803 37ImmunoChip
rs102275T/C chr11: 61314379 36ImmunoChip

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Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs615320rs102275rs10227587
rs60986688rs102275rs102275130
rs754897rs102275rs10227592
rs386511185rs102275rs102275142

Criteria

rs102275 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is in r2>0.8 with an index SNP 
Marker is an index SNP in a Region 
Marker is GW-Significant in a Study 

Functional Information

Gene function properties for rs102275 as derived from dbSNP:
  • in intron
Gene(s) at location of variation:  TMEM258 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs102275, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.