Overview

IDAllelesLocationGenome BuildSource
rs10849448A/Gchr12: 638418538dbsnp146
rs10849448A/G chr12: 6493351 37dbsnp146_grch37

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Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs58364318rs10849448rs10849448130

Criteria

rs10849448 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is GW-Significant in a Study 
Marker is an index SNP in a Region 

Functional Information

Gene function properties for rs10849448 as derived from dbSNP:
  • in intron
  • in 5prime utr
Gene(s) at location of variation:  LTBR 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs10849448, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.