Overview

IDAllelesLocationGenome BuildSource
rs11168249T/Cchr12: 4781458538dbsnp146
rs11168249T/C chr12: 48208368 37dbsnp146_grch37
rs11168249A/G chr12: 47814585 38ImmunoChip
rs11168249A/G chr12: 48208368 37ImmunoChip
rs11168249A/G chr12: 46494635 36ImmunoChip

Jbrowse

Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs61569777rs11168249rs11168249130

Criteria

rs11168249 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is an index SNP in a Region 
Marker is GW-Significant in a Study 

Functional Information

Gene function properties for rs11168249 as derived from dbSNP:
  • in 5prime gene region
  • in intron
Gene(s) at location of variation:  HDAC7 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs11168249, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.