Overview

IDAllelesLocationGenome BuildSource
rs12521868G/Tchr5: 13244870138dbsnp146
rs12521868G/T chr5: 131784393 37dbsnp146_grch37
imm_5_131812292T/G chr5: 132448701 38ImmunoChip
imm_5_131812292T/G chr5: 131784393 37ImmunoChip
imm_5_131812292T/G chr5: 131812292 36ImmunoChip

Jbrowse

Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs61166245rs12521868rs12521868130

Criteria

rs12521868 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is in r2>0.8 with an index SNP 
Marker is an index SNP in a Region 
Marker is GW-Significant in a Study 

Functional Information

Gene function properties for rs12521868 as derived from dbSNP:
  • in intron
Gene(s) at location of variation:  C5orf56 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs12521868, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.