Overview

IDAllelesLocationGenome BuildSource
rs151181T/Cchr16: 2847919638dbsnp146
rs151181T/C chr16: 28490517 37dbsnp146_grch37
imm_16_28398018T/C chr16: 28479196 38ImmunoChip
imm_16_28398018T/C chr16: 28490517 37ImmunoChip
imm_16_28398018T/C chr16: 28398018 36ImmunoChip

Jbrowse

Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs233646rs151181rs15118185
rs365094rs151181rs15118187
rs59390255rs151181rs151181130
rs386535076rs151181rs151181142

Criteria

rs151181 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is in r2>0.8 with an index SNP 
Marker is an index SNP in a Region 
Marker is GW-Significant in a Study 

Functional Information

Gene function properties for rs151181 as derived from dbSNP:
  • in intron
Gene(s) at location of variation:  CLN3  NPIPB8 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs151181, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.