Overview

IDAllelesLocationGenome BuildSource
rs2227564T/Cchr10: 7391334338dbsnp146
rs2227564T/C chr10: 75673101 37dbsnp146_grch37

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Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs17856426rs2227564rs2227564126
rs2228228rs2227564rs2227564110
rs111378844rs2227564rs2227564133
rs57705546rs2227564rs2227564130
rs56591699rs2227564rs2227564130

Criteria

rs2227564 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is an index SNP in a Region 
Marker is GW-Significant in a Study 

Functional Information

Gene function properties for rs2227564 as derived from dbSNP:
  • in intron
  • has reference
  • has non-synonymous missense
Gene(s) at location of variation:  C10orf55  PLAU 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs2227564, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.