Overview

IDAllelesLocationGenome BuildSource
rs2284553A/Gchr21: 3340438938dbsnp146
rs2284553A/G chr21: 34776695 37dbsnp146_grch37
rs2284553T/C chr21: 33404389 38ImmunoChip
rs2284553T/C chr21: 34776695 37ImmunoChip
rs2284553T/C chr21: 33698565 36ImmunoChip

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Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs61702344rs2284553rs2284553130

Criteria

rs2284553 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is an index SNP in a Region 
Marker is GW-Significant in a Study 

Functional Information

Gene function properties for rs2284553 as derived from dbSNP:
  • in intron
Gene(s) at location of variation:  IFNGR2 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs2284553, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.