Overview

IDAllelesLocationGenome BuildSource
rs2297441G/Achr20: 6369622938dbsnp146
rs2297441G/A chr20: 62327582 37dbsnp146_grch37
imm_20_61798026A/G chr20: 63696229 38ImmunoChip
imm_20_61798026A/G chr20: 62327582 37ImmunoChip
imm_20_61798026A/G chr20: 61798026 36ImmunoChip

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Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs60545163rs2297441rs2297441130
rs3171138rs2297441rs2297441106
rs57365409rs2297441rs2297441130

Criteria

rs2297441 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is an index SNP in a Region 
Marker is GW-Significant in a Study 

Functional Information

Gene function properties for rs2297441 as derived from dbSNP:
  • in 5prime gene region
  • in intron
  • in 3prime utr
Gene(s) at location of variation:  TNFRSF6B  RTEL1-TNFRSF6B  RTEL1 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs2297441, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.