Overview

IDAllelesLocationGenome BuildSource
rs2303759T/Gchr19: 4936579438dbsnp146
rs2303759T/G chr19: 49869051 37dbsnp146_grch37
rs2303759T/G chr19: 49365794 38ImmunoChip
rs2303759T/G chr19: 49869051 37ImmunoChip
rs2303759T/G chr19: 54560863 36ImmunoChip

Jbrowse

Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs59086630rs2303759rs2303759130
rs52827084rs2303759rs2303759128

Criteria

rs2303759 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is GW-Significant in a Study 
Marker is in r2>0.8 with an index SNP 
Marker is an index SNP in a Region 

Functional Information

Gene function properties for rs2303759 as derived from dbSNP:
  • in intron
  • has reference
  • has non-synonymous missense
Gene(s) at location of variation:  DKKL1 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs2303759, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.