Overview

IDAllelesLocationGenome BuildSource
rs2451258C/Tchr6: 15908556838dbsnp146
rs2451258C/T chr6: 159506600 37dbsnp146_grch37
imm_6_159426588T/C chr6: 159085568 38ImmunoChip
imm_6_159426588T/C chr6: 159506600 37ImmunoChip
imm_6_159426588T/C chr6: 159426588 36ImmunoChip

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Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs13201535rs2451258rs2451258123
rs17218022rs2451258rs2451258123
rs57157134rs2451258rs2451258130

Criteria

rs2451258 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is GW-Significant in a Study 
Marker is an index SNP in a Region 

Functional Information

Gene function properties for rs2451258 as derived from dbSNP:
  • in intron

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs2451258, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.