Overview

IDAllelesLocationGenome BuildSource
rs27434A/G,Tchr5: 9679380938dbsnp146
rs27434A/G,T chr5: 96129512 37dbsnp146_grch37
imm_5_96155268A/G chr5: 96793809 38ImmunoChip
imm_5_96155268A/G chr5: 96129512 37ImmunoChip
imm_5_96155268A/G chr5: 96155268 36ImmunoChip

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Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs58753129rs27434rs27434130

Criteria

rs27434 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is an index SNP in a Region 
Marker is GW-Significant in a Study 

Functional Information

Gene function properties for rs27434 as derived from dbSNP:
  • has synonymous
  • has reference
Gene(s) at location of variation:  ERAP1 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs27434, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.