Overview

IDAllelesLocationGenome BuildSource
rs2812378G/Achr9: 3471026338dbsnp146
rs2812378G/A chr9: 34710260 37dbsnp146_grch37
imm_9_34700260T/C chr9: 34710263 38ImmunoChip
imm_9_34700260T/C chr9: 34710260 37ImmunoChip
imm_9_34700260T/C chr9: 34700260 36ImmunoChip

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Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs16931795rs2812378rs2812378123
rs57427236rs2812378rs2812378130
rs386574189rs2812378rs2812378142

Criteria

rs2812378 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is in r2>0.8 with an index SNP 
Marker is an index SNP in a Region 
Marker is GW-Significant in a Study 

Functional Information

Gene function properties for rs2812378 as derived from dbSNP:
  • in 5prime gene region
Gene(s) at location of variation:  CCL21 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs2812378, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.