Overview

IDAllelesLocationGenome BuildSource
rs4976646T/Cchr5: 17736156938dbsnp146
rs4976646T/C chr5: 176788570 37dbsnp146_grch37
rs4976646T/C chr5: 177361569 38ImmunoChip
rs4976646T/C chr5: 176788570 37ImmunoChip
rs4976646T/C chr5: 176721176 36ImmunoChip

Jbrowse

Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs58876613rs4976646rs4976646130

Criteria

rs4976646 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is in r2>0.8 with an index SNP 
Marker is an index SNP in a Region 
Marker is GW-Significant in a Study 

Functional Information

Gene function properties for rs4976646 as derived from dbSNP:
  • in intron
Gene(s) at location of variation:  RGS14 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs4976646, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.