Overview

IDAllelesLocationGenome BuildSource
rs582757C/Tchr6: 13787668738dbsnp146
rs582757C/T chr6: 138197824 37dbsnp146_grch37
imm_6_138239517A/G chr6: 137876687 38ImmunoChip
imm_6_138239517A/G chr6: 138197824 37ImmunoChip
imm_6_138239517A/G chr6: 138239517 36ImmunoChip

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Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs58290415rs582757rs582757130
rs58927148rs582757rs582757130
rs386600060rs582757rs582757142

Criteria

rs582757 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is an index SNP in a Region 
Marker is GW-Significant in a Study 

Functional Information

Gene function properties for rs582757 as derived from dbSNP:
  • in intron
Gene(s) at location of variation:  TNFAIP3 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs582757, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.