Overview

IDAllelesLocationGenome BuildSource
rs7574865T/Gchr2: 19109990738dbsnp146
rs7574865T/G chr2: 191964633 37dbsnp146_grch37
imm_2_191672878T/G chr2: 191099907 38ImmunoChip
imm_2_191672878T/G chr2: 191964633 37ImmunoChip
imm_2_191672878T/G chr2: 191672878 36ImmunoChip

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Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs52795984rs7574865rs7574865128
rs57433953rs7574865rs7574865130

Criteria

rs7574865 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is in r2>0.8 with an index SNP 
Marker is an index SNP in a Region 
Marker is GW-Significant in a Study 

Functional Information

Gene function properties for rs7574865 as derived from dbSNP:
  • in intron
Gene(s) at location of variation:  STAT4 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs7574865, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.