Overview

IDAllelesLocationGenome BuildSource
rs8042861G/Tchr15: 9043410138dbsnp146
rs8042861G/T chr15: 90977333 37dbsnp146_grch37
rs8042861T/G chr15: 90434101 38ImmunoChip
rs8042861T/G chr15: 90977333 37ImmunoChip
rs8042861T/G chr15: 88778337 36ImmunoChip

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Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs60261176rs8042861rs8042861130
rs17262089rs8042861rs8042861123

Criteria

rs8042861 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is an index SNP in a Region 
Marker is GW-Significant in a Study 

Functional Information

Gene function properties for rs8042861 as derived from dbSNP:
  • in intron
Gene(s) at location of variation:  IQGAP1 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs8042861, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.