Overview

IDAllelesLocationGenome BuildSource
rs8070345T/Cchr17: 5973939638dbsnp146
rs8070345T/C chr17: 57816757 37dbsnp146_grch37
rs8070345A/G chr17: 59739396 38ImmunoChip
rs8070345A/G chr17: 57816757 37ImmunoChip
rs8070345A/G chr17: 55171539 36ImmunoChip

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Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs74256795rs8070345rs8070345131
rs17496285rs8070345rs8070345123
rs57088200rs8070345rs8070345130

Criteria

rs8070345 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is GW-Significant in a Study 
Marker is an index SNP in a Region 

Functional Information

Gene function properties for rs8070345 as derived from dbSNP:
  • in intron
Gene(s) at location of variation:  VMP1 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs8070345, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.